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Anxiety and Depression

Publications and Research

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01_19 Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depressionJJ Psych Behav Sci. 2019; 6(1): 25-31. Anxiety, Depression, Insomnia, First responder open
Morriss R, Xydopoulos G, Craven M, Price L, Fordham R. Clinical effectiveness and cost minimisation model of Alpha-Stim cranial electrotherapy stimulation in treatment seeking patients with moderate to severe generalised anxiety disorderJournal of Affective Disorders. 2019, June; 253:426-437. Anxiety, Cost minimisation
Kirsch TB, Kuhn J, Price LR, Marksberry J, Haltiwanger SG. A novel medical device that relieves anxiety, depression and pain while improving sleep in a population of teachersJournal of Depression and Anxiety. 2019; 8:334.
Pain, Anxiety, Depression open
Yennurajalingam S, Kang D-H, Hwu W-J, Padhye NS, Masino C, Dibaj SS, Liu DD, Williams JL, Lu Z, Bruera E. Cranial electrotherapy stimulation for the management of depression, anxiety, sleep disturbance, and pain in patients with advanced cancer: a preliminary study. Journal of Pain and Symptom Management.  2018, 55(2): 198–206. Cancer, Pain, Anxiety, Insomnia, Depression, CES open (abstract)
Hare JP, Misialek LH, Palis K and Wong C. Using cranial electrotherapy stimulation therapy to treat behavioral health symptoms in a combat operational setting. Military Medicine. 2016; 181(11):1410-1412. CES, Military Report
Mellen RR, Case J and Ruiz DJ. Cranial electrotherapy stimulation (CES) As a treatment for reducing stress and improving prefrontal cortex functioning in victims of domestic violence. International Association for Correctional and Forensic Psychology Newsletter. 48(3):12-15, 2016. CES, Violence, Victim, Anxiety Report
Rickabaugh K et al. A retrospective review of patient perception of Alpha-Stimulation treatment. Poster presented at The Military Health System Symposium in Kissimmee, Florida. 2016; August 15-18.  CES, Military Poster

Hill N. The Effects of Alpha Stimulation on Induced Anxiety. Electronic Theses and Dissertations 2015 CES, induced anxiety RCT
LU Ling, HU Jun. A comparative study of anxiety disorders treatment with Paroxetine in combination with cranial electrotherapy stimulation therapy. Medical Innovation of China, 11(08):080-082, 2014. CES, Paroxetine, Anxiety RCT

Barclay TH, Barclay RD. A clinical trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders, 164:171-177, 2014.  CES, Cranial Electrotherapy Stimulation, Anxiety, Depression RCT
Kirsch DL, Price LR, Nichols F, Marksberry JA and Platoni KT. Efficacy of Cranial Electrotherapy Stimulation for Anxiety, PTSD, Insomnia, and Depression: US Military Service Members and Veterans Self Reports. The United States Army Medical Department Journal.  October-December 2014:46-54. CES, Cranial Electrotherapy Stimulation, Anxiety, Depression, PTSD, Insomnia Report
02_13 Amr Bipolar.JPG
Amr, Mostafa, El-Wasify, Mahmoud, Elmaadawi, Ahmed, Roberts, Jeannie, and El-Mallakn, Rif. Cranial Electrotherapy Stimulation for the Treatment of Chronically Symptomatic Bipolar Patients.  Journal of ECT, 29(2): 31-32, 2013. CES, Cranial Electrotherapy Stimulation, bipolar RCT

Lee, S-H, Kim, W-Y, Lee C-H, Min, T-J, Lee Y-S, Kim J-H. Effects of cranial electrotherapy stimulation on preoperative anxiety, pain and endocrine response. Journal of International Medical Research, 41(6) 1788–1795, 2013. CES, Cranial Electrotherapy Stimulation, Preoperative Anxiety, Endocrine RCT

Koleoso ON, Osionwo HO, Akkhigbe. The role of relaxation therapy and cranial electrotherapy stimulation in the management of dental anxiety in Nigeria.  ISOR Journal of Dental and Medical Sciences, 2013, 10(4): 51-57. CES, Cranial Electrotherapy Stimulation, Dental, Anxiety RCT
Mellen, Ronald R. and  Mackey,Wade. Reducing Sheriff’s Officers’ Symptoms of Depression Using Cranial Electrotherapy Stimulation (CES): A Control Experimental Study.  The Correctional Psychologist, 41(1):9-15, 2009. CES, Cranial Electrotherapy Stimulation, Depression RCT
Mellen, Ronald R. and  Mackey, Wade. Cranial Electrotherapy Stimulation (CES) and the Reduction of Stress Symptoms in a Sheriff’s Jail Security and Patrol Offficer Population: A Pilot Study. AmericanJail’s, 11/12 2008: 32-38.  CES, Cranial Electrotherapy Stimulation, Stress RCT
07_08 Strentzsch Summ. Alpha Amylase, Co Strentzsch, Julie A. An examination of cranial electrotherapy stimulation (CES) on alpha-amylase levels, cortisol levels and state-trait anxiety scores in the chronically mentally ill.  Doctoral Dissertation, Saint Mary’s University, San Antonio, Texas, 2008. CES, Cranial Electrotherapy Stimulation, Cortisol, Alpha-Amylase, Anxiety, Mentally Ill RCT
Bystritsky, A., Kerwin, L., Feusner, J. A pilot study of cranial electrotherapy stimulation for generalized anxiety disorder. Journal of Clinical Psychiatry, 69:412-417, 2008. CES, Cranial Electrotherapy Stimulation, Anxiety open
Chen Yixin, Yu Lin, Zhang Jiuping, Li Lejia, Chen Tunong, Chen Yi. Results of cranial electrotherapy stimulation to children with mixed anxiety and depressive disorder. Shanghai Archives of Psychiatry, 19(4):203-205, 2007. CES, Cranial Electrotherapy Stimulation, Children, CCMD-3, Anxiety, Depression RCT
Lu XY, Wang AH, Li Y, Zhang JS, Liu BX. Safety and effectiveness of cranial electrotherapy stimulation in treating children with emotional disorders. Chinese Journal of Clinical Rehabilitation, 9(8):96-7, 2005. CES, Cranial Electrotherapy Stimulation, Children, CCMD-3, Anxiety, Depression open
Gilula, Marshall F. and Barach, Paul R. Cranial Electrotherapy Stimulation: a Safe Neuromedical Treatment for Anxiety, Depression or Insomnia. Southern Medical Journal. 2004; 97(12):1269-1270. CES, Cranial Electrotherapy Stimulation, Anxiety, Depression, Insomnia, safe, Side Effects Meta Analyses
Winick, Reid L. Cranial Electrotherapy Stimulation (CES): A Safe and Effective Low Cost Means of Anxiety Control in a Dental Practice. General Dentistry, 47(1):50-55, 1999.  CES, Cranial Electrotherapy Stimulation, Dental, Anxiety RCT
Voris, Marshall D. An Investigation of the Effectiveness of Cranial Electrotherapy Stimulation in the Treatment of Anxiety Disorders Among Outpatient Psychiatric Patients, Impulse Control Parolees and Pedophiles. Delos Mind/Body Institute Newsletter, Dallas and Corpus Cristi, Texas, 1995. CES, Cranial Electrotherapy Stimulation, Anxiety, Impulse Control RCT
Gibson, Thomas H. and O’Hair, Donald E. Cranial Application of Low Level Transcranial Electrotherapy vs. Relaxation Instruction in Anxious Patients.  American Journal of Electromedicine, 4(1):18-21, 1987. Doctoral dissertation (TG), California School of Professional Psychology, 152 pages, 1983. CES, Cranial Electrotherapy Stimulation, Anxiety, Relaxation RCT
Overcash, Stephen J. Cranial Electrotherapy Stimulation in Patients Suffering from Acute Anxiety Disorders.  American Journal of Electromedicine, 16(1):49-51, 1999. CES, Cranial Electrotherapy Stimulation, Anxiety open